Which source of supply is responsible for cradle to grave management of every Air Force weapon system?

The Air Force Materiel Command (AFMC) is the correct answer as it plays a crucial role in the cradle-to-grave management of every Air Force weapon system. This includes the entirety of a weapon system's lifecycle—from the initial research and development phase, through production and deployment, to eventual retirement and disposal.

AFMC's responsibilities encompass a wide range of functions including logistics, acquisition, and maintenance support, which facilitates the effective stewardship and longevity of weapon systems. Their involvement ensures that systems are managed efficiently and effectively, reflecting a commitment to operational readiness and sustainable resource management.

The other options, while important to the overall logistics and supply chain processes, do not cover the comprehensive lifecycle management aspect to the extent that AFMC does. For example, the Defense Logistics Agency focuses on logistics support and supply chain management, but it does not oversee the complete lifecycle of weapon systems. Similarly, the Logistics Support Agency and the Air Force Purchasing Office have specific roles that do not encompass the full cradle-to-grave management responsibility assigned to AFMC.